HONORS
GENETICS (BIOLOGY 350C) TOPIC SCHEDULE
FALL 2007
Tuesdays and Thursdays,
Dr. Bonnie Wood
See Key to Fonts on back of this paper
|
WEEK |
HOMEWORK |
TUESDAY
|
THURSDAY
|
|
1 |
Chs.
1, 10, 11(p.
298) Read
Syllabus/ Visit
the DNA model, Northern Maine Museum of Science |
8/28:
Three Areas of Genetics •
Find
Your Learning Group/Introductions
•
Laboratory Use Agreement •
How
to Extract and Spool DNA in your
Kitchen •
Case
Study: A Sickeningly Sweet Baby Boy: A Case Study on Recessive Inheritance in
Inbred Populations Student-led teaching model
signups
|
8/30: DNA Structure (Outline 1) ·
Teaching
Outside the (Cereal) Box: DNA Structure (Grade the professor! Demonstration
of a teaching model) ·
Polarity
and Antiparallel Structure ·
Properties
of DNA ·
Video: “Photo 51” |
|
2 |
Chs.
11, 12 |
9/4: Chromosome Structure (Outline 2) ·
Chromatin To Chromosome Model ·
The Size Of The E. coli Genome ·
Giant (Polytene) Chromosomes |
9/6:DNA Replication (Outline 3) ·
Teaching Outside the (Cereal) Box: DNA Replication ·
Modeling the Classic Meselson & Stahl
Experiment + Meselson-Stahl Experimental Simulation Using Lego™ Building
Blocks ·
Modeling DNA Replication |
|
3 |
Chs.
13, 14, 15 |
9/11:Transcription and RNA (Outline 4) ·
Prep
for Week 5: Pour LB agar plates and streak and restreak Serratia during the week to achieve
all white/yellow cultures. Incubate at 37oC ·
Teaching Outside the (Cereal) Box: Transcription ·
DNA Puzzle Kit: Student Worksheets -
DNA:
The Genetic Code, RNA: The Code Transcribed, & Protein Synthesis |
9/13: Genetic
Code and Translation (Outline 5) ·
Teaching Outside the (Cereal) Box: Translation ·
Modeling Protein Folding ·
Demonstrating Translation with a
Student-Centered Activity ·
A Working Model of Protein Synthesis
Using Lego™ Building Blocks ·
Restreak Serratia during the week to achieve
all white/yellow cultures. Incubate at 37oC |
|
4 |
|
9/18: Genetic Code and Translation (Outline 5) ·
Restreak and incubate the white/yellow Serratia at two different temperatures. ·
Case
Study: Tazswana’s Story: How
Alternative mRNA splicing Leads to Genetic Disease and Cure ·
Guest Speaker: Donald Sawyer, M.D.: “”Beta-Thalassemia in |
9/20: TEST (Outlines 1-5) ·
Prepare plates A and B of Serratia according to Outline 6
instructions. •
Prepare tobacco solution |
|
5 |
|
9/25: Gene Mutations
and DNA Repair (Outline 6) •
Regulation of Gene Expression using S. marcescens •
Tobacco-Induced Mutations-Class 1 •
Mutations and Expression of the Beta-Globin Gene •
Video: Accidents of Creation |
9/27: Gene Mutations
and DNA Repair (Outline 6) •
Tobacco-Induced Mutations-Class 2 •
For
Colony Transformation: use previously-poured agar to streak E. coli
and incubate •
Video:
Bacterial Transformation •
Case Study: A Right to
Her Genes |
|
6 |
Due
10/2:
Read Case
Study: Nińos Desaparecidos and be prepared to discuss/ Submit book review
title |
10/2: Bacterial and Viral Genetics (Outline 7) ·
Colony
Transformation ·
Pour
electrophoresis gels for 10/16 laboratory ·
Case
Study: Nińos Desaparecidos ·
Video:
The Dirty War |
10/4:
Recombinant DNA Technology (Outline 8) ·
Linguini Models of Molecular Genetic
Mapping & Fingerprinting ·
Teaching DNA Fingerprinting Using a
Hands-On Simulation ·
Recombinant DNA Paper Model Simulation ·
PCR Tutorial ·
Case Study: The Case of the Druid Dracula |
|
UMPI FALL BREAK: NO CLASSES 10/8 – 10/12 |
|||
|
7 |
Take home portion of test: FrankenFoods OR Taco
Shells Case Study |
10/16: Recombinant DNA Technology (Outline 8) ·
Teaching Outside the (Cereal) Box: Restriction
Digestion and Polymerase Chain Reaction ·
Guest Speaker: Jason Johnson, Ph.D., Assistant
Professor of Wildlife Ecology: “ Using PCR to Determine Sex of Wood Thrush
Nestlings“ |
10/18: TEST
(Outlines 6-8) [10/19: Dr. Wood
submits midterm grades] |
|
WEEK |
HOMEWORK |
TUESDAY
|
THURSDAY
|
8 |
Due
10/23: Human
Genome Project homework |
10/23: Genomics
(Outline 9) Meet
in Computer Lab, Folsom 101B
·
Case Study: Genetic Testing and Breast Cancer: Is a
Little Knowledge a Dangerous Thing? ·
Guest
Speaker: “BLASTing Can be a Blast!”, Kim Borges-Therien, Ph.D., Associate
Professor of Environmental Studies, UMFK |
10/25: Genomics (Outline 9) ·
Teaching Outside the (Cereal) Box (Sequencing,
Hybridization & Probing) ·
A Demonstration of Automated DNA
Sequencing ·
Microarrays Made Simple: “DNA
Chips” Paper Activity ·
Prepare
onion bulbets for sprouting |
|
9 |
Due
10/30: Cut
out pink and blue chromosomes & bring to class with 6 paperclips/ Submit book review title |
10/30: Eukaryotic Cell Reproduction (Outline 10) Mitosis sections of: ·
Chromosome socks ·
Hands-on Activities that Relate Mendelian
Genetics to Cell Division ·
Students as Human Chromosomes ·
Mitosis
in Plants and Animals |
11/1: Eukaryotic Cell Reproduction (Outline 10) Meiosis sections of: ·
Chromosome
socks ·
Hands on Activities that Relate Mendelian
Genetics to Cell Division ·
Students as Human Chromosomes ·
Meiosis
and Fertilization ·
Gamete
Problem Sets ·
Case
Study: Bringing Back Baby Jason |
|
10 |
Chs.
3, 5 |
11/6:Principles of Heredity (Outline 11) ·
Cookie-Ases: Interactive Models for
Teaching Genotype-Phenotype Relationships ·
Using Manipulatives to Teach Basic
Mendelian Genetics Concepts ·
Case
Study: Woe to That Child: A Case of Cystic Fibrosis |
11/8: Principles of Heredity (Outline 11) ·
ABO/Rh Blood-Typing Model ·
Simulated
Blood Typing: Whodunit ·
Epistasis
in Labrador Retrievers |
|
11 |
Ch.
4, 5 By
11/13: Visit color-blindness
exhibit, Northern Maine Museum of Science |
11/13: Second Biennial Genetics Consortium:
UMPI/UMFK At Eureka Hall, Stockholm 11:00 AM-4:00 PM Sex-Related Inheritance (Outline 12) ·
Case
Study: In the Genes or in the Jeans? ·
Video:
Birth, Sex, and Death |
11/15: Use Of Probability Formulations And The Chi-Square Test
(Outline 13)
·
Taste
Test ·
Predicting
Probabilities in Dihybrid and Multifactorial Crosses ·
Case
Study: Hemophilia: The Royal Disease |
|
12 |
| ||